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Observe INR far more often if coadministered with inhibitors of these isoenzymes and change warfarin dose if desired.
itraconazole will enhance the amount or impact of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
For oral dosage form (tablets): For narcolepsy or obstructive sleep apnea/hypopnea syndrome: Older people and youngsters 17 a long time of age and older—200 milligrams (mg) once daily, each morning. Your physician may raise your dose as needed. Teenagers and youngsters younger than seventeen decades of age—Use and dose needs to be determined by your physician.
When a doctor prescribes modafinil, they supply detailed Guidelines on dosages for their unique use.
Provigil will likely be taken Just about every morning to stop daytime sleepiness, or one hour ahead of the get started of a work shift to treat perform-time sleep Problems.
eslicarbazepine acetate will increase the amount or outcome of modafinil by influencing hepatic enzyme CYP2C19 metabolism. Use Warning/Watch.
Modafinil may minimize serum concentrations of other prescription drugs to some clinically sizeable extent, together with the next:
In obstructive rest apnea (OSA), doses around 250 mg/day have already been properly-tolerated but there is no regular proof of more reward outside of the a hundred and fifty mg/working day.
Any dose that's read more fifty mg or much less is taken into account a microdose— meaning the dose is beneath the therapeutic threshold.
voriconazole will raise the level or influence of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
Allergic reactions including rash, angioedema, anaphylaxis, and Stevens–Johnson syndrome might be brought on by an immunological response to modafinil or its metabolites.
This drugs is on the market only with all your health care provider's prescription. This products is available in the subsequent dosage varieties:
Exactly the same can take place with modafinil— Which explains why it’s greatest to be sure there won't be any challenges in advance of leaping straight into a substantial 400 mg dosage.